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Allopurinol or Febuxostat: A Side-by-Side Look at Two Leading Gout Medications

Allopurinol or Febuxostat: A Side-by-Side Look at Two Leading Gout Medications

When a rheumatologist prescribes urate-lowering therapy, the choice between allopurinol and febuxostat is rarely straightforward. This detailed comparison examines how each xanthine oxidase inhibitor performs across efficacy, safety, cost, and patient-specific factors—helping you arrive at your next appointment better informed.